Sampling designs for rare time-dependent exposures: a comparison of the nested exposure case-control design and exposure density sampling
نویسندگان
چکیده
منابع مشابه
Comparison of nested case-control and survival analysis methodologies for analysis of time-dependent exposure
BACKGROUND Epidemiological studies of exposures that vary with time require an additional level of methodological complexity to account for the time-dependence of exposure. This study compares a nested case-control approach for the study of time-dependent exposure with cohort analysis using Cox regression including time-dependent covariates. METHODS A cohort of 1340 subjects with four fixed a...
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BACKGROUND The nested case-control design can be a very efficient approach to an epidemiological investigation. In order to obtain unbiased estimates of relative risk, controls should be selected by incidence density sampling, which involves matching each case to a sample of those who are at risk at the time of case occurrence. METHODS This paper presents a simple computer program for inciden...
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K. Ohneberg1,2; M. Wolkewitz1,2; J. Beyersmann3; M. Palomar-Martinez4,5; P. Olaechea-Astigarraga6; F. Alvarez-Lerma7; M. Schumacher1 1Institute for Medical Biometry and Statistics, Medical Center University of Freiburg, Freiburg, Germany; 2Freiburg Center for Data Analysis and Modelling, University of Freiburg, Freiburg, Germany; 3Institute of Statistics, Ulm University, Ulm, Germany; 4Hospital...
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A stratified version of nested case-control sampling which we call "countermatching" is presented. This design uses data available for all cohort members to obtain a sample for collecting additional information in a case-control substudy. Hitherto the only stratified sampling design for such studies has involved matching of controls to cases with respect to confounding variables. However, in so...
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ژورنال
عنوان ژورنال: Epidemiology and Infection
سال: 2021
ISSN: 0950-2688,1469-4409
DOI: 10.1017/s095026882100090x